Are any forum members using PlayOnLinux?
Never got it working..
If using wine, then directly -> just doubleclick the exe files (or their apple counterpart).
Might require to associate the *.exe files with wine on the first time use though.
hth
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I haven't used it for years I've found WINE more than capable these days
Yup, I tried it. I "installed" Prehistorik. It was a cool game back in the DOS' days 
Worked well.
I also use PS CS5, mirc, Total Commander with wine.
I would like to use, but installer tells me if I install, it will remove my (non free) device driver (NVIDIA) for my HDMI monitor, and I would consequentially also lose my Hi DEF sound. Not prepared to pay such a price, and have not (yet) seen way round this.