I think juggernautjoee is looking for something more like:
awk '/^02,193631306,000300032,1,/{$0 = substr($0,1,32) "2400" substr($0,37)}1' file
or if the line to be changed is always line #2:
awk 'NR==2{$0 = substr($0,1,32) "2400" substr($0,37)}1' file
but the specification of the problem is not clear. If the desire is to change the 6th field instead of to change the 33rd through the 36th characters on the line, then use:
awk -F, '/^02,193631306,000300032,1,/{$6 = 2400}1' OFS=, file
or:
awk -F, 'NR==2{$6=2400}1' OFS=, file
With the sample input provided, all of the above produce the output:
01,000300032,193631306,190619,0640,1,80,,2/
02,193631306,000300032,1,190618,2400,CAD,2/