remove and replace text in a file

Hello all,
How would I go to a particular line in a file and remove certain text from it and replace with something that I want it to be there.

like: file /etc/abc
now look for line HOME="/export/xyz" in /etc/abc
and then replace with HOME=/"export/xyz1"

thanks in advance guys.

sed 's;HOME="/export/xyz" ;HOME=/"export/xyz1;"' /etc/abc > /etc/abc.new