Modification in configuration file to disable a particular user

Please anyone can tell me what is the procedure to perform the required modifications in configuration files to disable a particular user???

Depending on the OS - the usermod command can lock accounts. You can also change the login shell to /bin/false or something.

Most Unix/Linux OS

Lock account:

passwd <username> -l

unlock account:
passwd <username> -u

vipw

and edit the password entry belonging to that user. Either (1) remove the line, (2) change the shell to /bin/false, or (3) change the password field to "x".

There are other possibilities that are OS-specific, as Frank said. In Linux, you can look at the files in /etc/security.