With so many different flavors of UNIX and Linux available in the world, choosing the best one for yourself, your family, or for your organization can be such an overwhelming and rather difficult decision to make! 
If you were a salesman and you had to decide the best UNIX/Linux distro for each of your individual customers based on how it was going to be used, which would you generally recommend for the following applications (you don't have to answer all of them, just the one's that you are sure of ;)):
- Home
- Home Office
- Small Businesses (under 400 employees)
- Medium-Sized Businesses (400-2.000 employees)
- Large Businesses & Enterprises (over 2,000 employees)
- Small Nonprofit Organizations
- Large Nonprofit Organizations
- Education (Grade School)
- Higher Education
- Healthcare Institution
- Government Agency
- Military
- High-End Desktop
- Mid-Range Desktop
- Low-End Desktop
- HTPC (Home Theatre)
- High-End Notebook
- Mid-Range Notebook
- Low-End Notebook
- Tablet PC
- Sub-Notebook Computer
- Pocket PC/Smartphone
- Palmpilot/Smartphone
- XBox
- Playstation 2/3
- High-End Workstation
- Mid-Range Workstation
- Low-End Workstation
- Application Server
- Audio/Video Server
- Chat Server
- FTP Server
- IRC Server
- Mail Server
- News Server
- Proxy Server
- Telnet Server
- Web Server
- Beginner
- Intermediate User
- Advanced User
- Expert User
- Rich Customer ($$$)
- Value-Minded Customer
- Budget-Minded Customer
- Student (Grade School)
- Higher Education Student
- Office User
- Internet User
- Light Gamer
- Heavy Gamer
- Movie/Music Lover
- Multimedia Content Creator
- CAD User
- Programmer
- Hacker
- Do-It-All User
- BEST All-Around UNIX/Linux Distro
- WORST All-Around UNIX/Linux Distro
Whew! That's a lot of different applications! I think I pretty much covered them all. If I happened to have missed anything or something just does not make sense to you, feel free to post a suggestion and I might edit this list. 