Apply SeLinux policy to *nix device files

If its possible to apply SELinux policies to unix device files, would that be a problem?

I would like to apply a policy to a process and enforce what it can communicate with device-wise (eg. physical network interface port) based on that policy.

Would think that the "selinux-policy-mls" tool could give me that level of segmentation with SELinux?

Thoughts/suggestions?