Connect C#(App) + Exim en Centos

Hi everyone,

Today i'm faceing a problem, that really hope for some help.

I'm working in a Web application developed in C#(DB SQL Server 2012, IDE VS 2010), so i've hired two VPS (Virtual Private Server), one with Windows Server 2012 where it's running my app and the other VPS in Centos.
Well, i really need to know how can i connect my Web application by code with the Exim which it's running in Centos.
My web application try to send a lot of mails (thoundsands), that's why i'm trying to use Exim.
I've searched information about it, but i wasn't able to found anything.

Any Idea Pleaseeeeee?

The language is usually irrelevant at run time. It is hard to envision your architecture. You might want to buffer emails into an RDBMS or directory and have one or more daemons sending emails.